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Mayo Regional Hospital is a non-profit, 25-bed critical access hospital located in Dover-Foxcroft, the county seat of Piscataquis County.

Mayo Regional opened in 1978 and is governed by Hospital Administrative District 4, which was established by 12 towns to serve the healthcare needs of residents in a three-county area of rural central Maine.

Mayo Hospital has 22 physicians and 375 staff members dedicated to providing acute medical/surgical care, intensive care, surgical services and obstetrics in an inpatient setting, as well as a wide array of outpatient services.

Mayo Practice Associates, a department of the hospital, owns and operates eight physician practices in Corinna, Dexter, Dover-Foxcroft, Guilford and Milo.